【TITLE & POSITION】Tian Tian, Associate Professor, Master’s Supervisor

【ACADEMIC APPOINTMENTS】Committee Member of the Organoid and Organ-on-a-Chip Committee, Chinese Society of Toxicology; Committee Member of the Neural Regeneration and Tissue Repair Committee, Chinese Research Hospital Association

【CONTACT INFORMATION】E-mail: tiantian@cqu.edu.cn

【PERSONAL PROFILE】

Dr. Tian Tian received her Ph.D. in Biomedical Engineering from Southeast University in 2014. During her doctoral training, she was supported by the China Scholarship Council as a joint Ph.D. student at Harvard Medical School, where she conducted research on organ-on-a-chip systems. She will carry out visiting research at the University of Cambridge from 2026 to 2027.

Her research focuses on organoid-on-a-chip technologies and multi-organ interaction models for neurological disease modelling and drug evaluation. In recent years, her work has centered on brain organoid-on-a-chip systems and peripheral organ–brain axis microphysiological platforms, including integrated in vitro models of brain, intestine, heart and skin.

She has led 9 national and provincial-level research projects, including the National Natural Science Foundation of China (Young Scientists Fund), subprojects of the National Key R&D Program of China, and projects supported by the Chongqing Natural Science Foundation. She has published more than 20 papers in journals such as Advanced Healthcare Materials and Experimental Neurology, and contributed to 4 academic monographs and textbooks.

She holds 7 authorized patents, 3 of which have been successfully transferred. A brain multi-organ chip system developed under her leadership received investment support from the Chongqing Seed Fund and was reported by Chongqing Daily and Hualong Net. She teaches undergraduate and graduate courses including Physiology and Anatomy, Introduction to Neural Engineering, and Academic Writing and Research Ethics.

【RESEARCH INTERESTS】

1. Brain organoid-on-a-chip systems for neurological disease modelling

2. Peripheral organ–brain axis microphysiological systems and multi-organ interaction platforms

3.Biomimetic organ-on-a-chip technologies for drug evaluation and translational applications

【REPRESENTATIVE PUBLICATIONS】

1. Liu J, Li Q, Zhu H, Li AQ, Geng BY, Li ZA, Tian T*. Suspension culture with uniform shear stress in brain organoids-on-a-chip for modelling Alzheimer’s disease.Advanced Healthcare Materials, 2026.

2. Liu J, Lu R, Zheng X, Hou W, Zhao H, Tian T*. Establishment of gut-on-a-chip device with controllable oxygen gradients to study the contribution of Bifidobacterium bifidum to inflammatory bowel disease.Biomaterials Science, 2023.

3. Gong J, Meng T, Yang J, Hu N, Zhao H, Tian T*. Three-dimensional in vitro tissue culture models of brain organoids.Experimental Neurology, 2021.

4. Li X, Tian T*. Phytochemical characterization of Mentha spicata under differential drying conditions and nephrotoxicity screening using organ-on-a-chip platforms.Frontiers in Pharmacology, 2018.

5.Tian T, Liu J, Zhu H. Organ Chips and Visualization of Biological Systems. In:Visualized Medicine.Springer, 2023.