【Title and Position】

Associate Professor; Doctoral Supervisor; Deputy Department Chair

【Academic and Professional Appointments】

Member, Laser Medicine Committee, Chinese Optical Society; Council Member and Deputy Chair, Chongqing Society for Molecular Biology and Biochemistry; Standing Committee Member, Dermatological Aesthetics Committee, Chongqing Health Promotion and Health Education Society; Member, Chongqing Integrated Traditional Chinese and Western Medicine Anti-Aging Committee; Young Editorial Board Member, Western China Quality Education.

【Email】qiaolixie@cqu.edu.cn；https://bio.cqu.edu.cn/info/1242/5571.htm

【Biography】

Dr. Qiaoli Xie received her Ph.D. in Biology from Chongqing University and completed postdoctoral training at Cornell University and Xi’an Jiaotong University. She was awarded the Excellent Doctoral Dissertation Award of Chongqing. She has led or participated in 12 national, provincial, and ministerial research projects, including projects funded by the National Natural Science Foundation of China, the National Key R&D Program of China in Green Biomanufacturing, the General Program of the Chongqing Natural Science Foundation, and the Chongqing Innovation Program for Returned Overseas Scholars. She has received two Second Prizes of the Chongqing Natural Science Award. Dr. Xie has published more than 40 research articles in high-impact SCI journals, includingCell Reports and Journal of Advanced Research. One of her papers has been recognized as an ESI Highly Cited Paper in the top 1%. She has been granted three authorized invention patents. She has also led one Ministry of Education graduate engineering case project, contributed three cases to the National Graduate Teaching Case Database, and served as associate editor-in-chief of the textbook Experimental Techniques in Molecular Biology. She is a Chief Expert for Graduate Engineering Cases of the Ministry of Education. She has received several honors, including Excellent Graduate Supervisor Team of Chongqing, Leader of a First-Class Undergraduate Course of Chongqing, Teaching Master of Chongqing University,“Huang Shanglian”Academician Innovation Individual Award of Chongqing University, Outstanding Communist Party Member of Chongqing University, Second Prize in the Young Faculty Teaching Competition of Chongqing University, Advanced Worker of Chongqing University, and two First Prizes in the Young Faculty Teaching Competition of the School of Bioengineering. Dr. Xie has supervised students who have won the Second Prize in the National College Student Life Science Competition and published a high-level JCR Q1 SCI paper. Her students have also received awards in the“Challenge Cup”competition, key support in theChina International College Students’ Innovation and Entrepreneurship Program, bronze awards, and other honors. She teaches undergraduate and graduate courses, including Cell Engineering, Experimental Techniques in Cell and Genetic Engineering, Transgenic Detection and Safety Evaluation, Modern Biological Experimental Theory and Techniques, Development and Utilization of Microbial Resources, and Protein Biology.

【Research Interests】

1. Skin Diseases and Wound Repair

Elucidating the pathological molecular mechanisms of skin diseases to provide a theoretical basis for clinical treatment and dermatological aesthetics; investigating the mechanisms of skin aging, wound repair, and regeneration to promote the regeneration of skin appendages after repair.

2. Hair Regeneration and Hair Repigmentation Mechanisms

Investigating the molecular regulatory mechanisms underlying hair follicle development, hair cycle transition, and post-injury regeneration to provide theoretical support for the prevention and treatment of hair-related disorders such as alopecia; elucidating the cell fate regulation and microenvironmental mechanisms involved in hair graying and repigmentation to promote hair follicle functional restoration and improve the quality of hair regeneration.

3. Skin Organoids and Applications in Skin and Hair Research

Establishing physiologically relevant skin and hair follicle organoid models as novel experimental platforms for studying skin and hair development, disease initiation, and progression; advancing the application of skin organoids in mechanistic studies, drug screening, regenerative medicine, and precision therapy to support basic research and clinical translation in skin and hair biology.

4. Biomanufacturing and Synthetic Biology

Studying the biosynthesis, metabolic regulation, and biomanufacturing applications of important natural products. Using microorganisms and cells as chassis, this research aims to reveal the biosynthetic and regulatory mechanisms of important nutritional chemicals and to construct cell engineering systems, thereby providing scientific support for clinical therapy, food nutrition, and drug development.

【Representative Publications】

1. Zhou S, Li Z, Li X, Ye Y, Wang M, Jiang J, Tao L, Wang Y, Tung CT, Chung Y, Kim E, Shen X, Xu X, Xiang X, Xie Q, Zhang J, Wu W, Lin X, Chuong CM, Lei M. Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging.J Adv Res(IF:13). 2025 Apr; 70:339-353.

2. Jiang J, Shao X, Liu W, Wang M, Li Q, Wang M, Xiao Y, Li K, Liang H, Wang N, Xu X, Wu Y, Gao X, Xie Q, Xiang X, Liu W, Wu W, Yang L, Gu ZZ, Chen J, Lei M. The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis.Cell Rep(IF: 6.9). 2024 Jul 23;43(7):114513.

3. Liu W, Jiang J, Li Z, Xiao Y, Zhou S, Wang D, Zou Y, Liu T, Li K, Liang H, Wang N, Xiang X, Xie Q, Zhan R, Zhang J, Zhou X, Yang L, Chuong CM, Lei M. Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cells. Theranostics(IF: 13.3). 2024 May 27;14(8):3339-3357.

4. Wang D, Jiang J, Wang M, Li K, Liang H, Wang N, Liu W, Wang M, Zhou S, Zhang M, Xiao Y, Shen X, Li Z, Wu W, Lin X, Xiang X, Xie Q, Liu W, Zhou X, Tang Q, Zhou W, Yang L, Chuong CM, Lei M. Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism.Research (IF:10.9). 2024 Aug 1;7:0433.

5. Wang M, Wang M, Jiang J, Li K, Liang H, Wang N, Zou Y, Wang D, Zhou S, Tang Y, Wu W, Qiu W, Li X, Wang X, Xie Q, Xiang X, Zhou W, Yang L, Chuong CM, Lei M. THSD4 promotes hair growth by facilitating dermal papilla and hair matrix interactions.Theranostics (IF: 13.3). 2025 Feb 25;15(8):3571-3588.